Profil Kadar Malondialdehida, Glukosa dan Kolesterol Pada Tikus Putih yang Terpapar Asap Rokok
DOI:
https://doi.org/10.30872/j.trop.pharm.chem.v3i4.19Keywords:
Malondialdehyde, glucosa, cholesterolAbstract
Cigarette smoke is one of the potential of exogenous free radicals which can weaken antioxidant system so that can increase free radicals levels in the body. The increasing of free radicals can accelerating damage to cells that interfere with the metabolism in the body. This study aimed to determine whether free radicals from cigarette smoke can affect glucose and cholesterol levels in experimental animals. This research used male-2-old-month-rats that have weigth ± 200 grams and exposed to cigarette smoke as much as 1 stick every morning and afternoon for 7 days . The MDA levels was analyzed with Thiobarbituric Acid Reactive Substance (TBARS) method by spectrophotometer UV-Vis in χ =531 nm, whereas glucose and cholesterol were measured using a test strip. The results of MDA increased 6x first level after exposed to cigarette smoke, glucose level increase 1,5x frist level and cholesterol deacrease 0,25x after exposed to cigarette smoke.
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