Antioxidant Test of Ethanol Extract of Purple Passion Fruit Leaves (Passiflora edulis Sims var edulis) from Tenggarong City, Kutai Kartanegara Regency

Chintia Carollin; Viriyanata Wijaya; Riki

doi:10.30872/jtpc.v9i1.288

Authors

Chintia Carollin Department of Pharmacy, Faculty of Pharmacy, Mulawarman University, Samarinda, Indonesia Program of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia Author
Viriyanata Wijaya Department of Pharmacy, Faculty of Pharmacy, Mulawarman University, Samarinda, Indonesia Author
Riki Department of Pharmacy, Faculty of Pharmacy, Mulawarman University, Samarinda, Indonesia Author

DOI:

https://doi.org/10.30872/jtpc.v9i1.288

Abstract

Antioxidants are compounds that have the ability to reduce free radicals. Antioxidants are obtained from secondary metabolites such as flavonoids. One of the plants that contain flavonoids is purple passion fruit leaves (Passiflora edulis Sims var edulis). This study aims to determine the percentage of yield obtained from the soklet extraction of purple passion fruit leaves using 96% ethanol solvent, and to determine the IC50 of the extract. Percent yield done by calculating the weight of extract divided by the weight of the simplisia and multiplied by one hundred percent, obtained a percent yield of 18.6% show a good yield. Antioxidant activity test using DPPH (2,2- diphenyl-1-picrylhydrazyl) method, calculate the IC50 value, where ascorbic acid is used as a positive control. The results of the antioxidant activity test of extract ethanol purple passion fruit leaves showed very strong activity with IC50 value of 26,37 ppm and ascorbic acid IC50 value of 6,03 ppm.

Downloads

Download data is not yet available.

References

[1] E. Gultom, D. Nurfadhilah, and R. Lifiani, “Uji Aktivitas Analgesik Ektrak Etanol Daun Markisa (Passiflora edulis Simsss) Terhadap Mencit Putih Jantan (Muss mucculus) Dengan Metode Plat Panas,” Farmanesia, vol. 10, no. 2, 2023.

[2] Mukhriani, “Ekstraksi, Pemisahan Senyawa, Dan Identifikasi Senyawa Aktif,” Jurnal Kesehatan, vol. VII, no. 2, 2014.

[3] C. Zehiroglu and S. B. Ozturk Sarikaya, “The importance of antioxidants and place in today’s scientific and technological studies,” Nov. 01, 2019, Springer. doi: 10.1007/s13197-019-03952-x.

[4] J. Flieger, W. Flieger, J. Baj, and R. Maciejewski, “Antioxidants: Classification, Natural Sources, Activity/Capacity Measurements, And Usefulness For The Synthesis Of Nanoparticles,” Aug. 01, 2021, MDPI AG. doi: 10.3390/ma14154135.

[5] N. K. Nisa, E. Marliana, and Erwin, “Potensi Aktivitas Antioksidan Ekstrak Metanol Daun Sungkai (Peronema canescens Jack.) Potential Antioxidant Activity Of Methanol Extract Of Sungkai Leaves (Peronema canescens Jack.),” Jurnal Atomik, vol. 9, no. 1, pp. 19–24, 2024, doi: 10.30872/ja.v9i1.1277.

[6] A. Guntarti, R. Yuningtyas, H. Susanti, and ; Zainab, “Jurnal Farmasi Sains dan Praktis Analysis Of Total Flavonoid Level And Antioxidant Activity Test Purple Cabbage (Brassica Oleracea L. Var. Capitata F. Rubra) And White Cabbage (Brassica Oleracea L. Var. Capitata F. ALBA) Ethanol Extract Using Dpph Method (1,1-Difenil-2-Pikrilhidrazil),” 2021. [Online]. Available: http://journal.ummgl.ac.id/index.php/pharmacy.

[7] Kementerian Kesehatan Republik Indonesia, “Farmakope Herbal Indonesia Edisi II,” 2017.

[8] N. Tapalina, Tutik, and G. A. R. Saputri, “Pengaruh Metode Ekstraksi Panas Terhadap Aktivitas Antioksidan Ekstrak Kulit Bawang Merah (Allium cepa L.),” Jurnal Ilmu Kedokteran dan Kesehatan, vol. 9, 2022.

[9] D. R. Badaring et al., “Uji Ekstrak Daun Maja (Aegle marmelos L.) terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus Indonesian Journal Of Fundamental Sciences (IJFS),” Indonesian Journal of Fundamental Sciences, vol. 6, no. 1, 2020.

[10] W. F. Dewatisari, L. Rumiyanti, and I. Rakhmawati, “Rendemen dan Skrining Fitokimia pada Ekstrak Daun Sanseviera sp.,” Jurnal Penelitian Pertanian Terapan, vol. 17, no. 3, p. 197, Jan. 2018, doi: 10.25181/jppt.v17i3.336.