Jamur Endofit, Biodiversitas, Potensi dan Prospek Penggunaannya Sebagai Sumber Bahan Obat Baru
Keywords:
Endhophytes, genetic transfer, biodiversityAbstract
Endhophytes microbes are microbes that live in colonies formed in plant tissues without harming its host plant. Endhophytes was first reported in 1904. Each higher plants may contain some Endhophytes microbes that produce secondary metabolites as a product of coevolution or genetic transfer occurred (genetic recombination) from its host plants to microbial Endhophytes. Endhophytes originating from areas with high biodiversity have the potential to generate chemical diversity is also high and has a future economic prospects.
References
Aminullah E., 1985. Perkembangan Penerapan Bioteknologi dan Rekayasa Genetik Dalam Kesehatan. Cermin Dunia KedokteranNo. 38: 52-55
Gunatilaka A.A., 2006.Natural Products from Plant-Associated Microorganism: Distribution, Structural Diversity, Bioactivity, and Implications of Their Occurrence. J. Nat. Prod. 2006. 69: 509-526
Lu, H.; Zou, W.X.; Meng, J.C.; Hu, J.; & Tan, R.X. 2000, New Bioactive Metabolites Produced by Colletotrichum sp., an Endophytic Fungus in Artemisia annua. Plant Sci. 151: 73-76
Maksum, R. 2005,Peranan Bioteknologi dan Mikroba Endofit Dalam Perkembangan Obat Herbal. Maj. Ilmu Kefarmasian Indonesia.Vol.II, No.3. Desember 2005: 113-126
Prasetyoputri, A.; & Atmosukarto, I. 2006, Mikroba Endofit: Sumber Molekul Acuan Baru yang Berpotensi.BioTrends. Vol I. No.2. 2006: 13-15
Proksch, P.; Edrada, R.A.; & Ebel, R. 2003, Review: Drugs from the Sea – Opportunities and Obstacles.Mar. Drugs 1, 5-17.
Schulz, B.; & Boyle, C. 2006,What Are Endophytes? dalam: Schulz, B.; Boyle, C.; & Sieber, T.N. (Eds.). Soil Biology. Volume 9. Microbial Root Endophytes. Springer-Verlag. Berlin Heidelberg. 2006: 1-13.
Strobel, G.A. 2002,Microbial gifts from rain forests.Can. J. Plant Pathol. 24: 14-20.
Strobel, G.A.; & Daisy, B. 2003,Bioprospecting for Microbial Endophytes and Their Natural Products. Microbiol.and Mol. Biology Rev. Dec 2003. Vol.67. No. 4: 491-502.
Strobel, G.A.; Daisy, B.; Castillo, U.; & Harper, J.2004,Natural Product from Endophytic Microorganism. J. Nat. Prod. 2004. 67: 257-268
Strobel, G.A.; Miller, R.V.; Miller, C.; Condron, M.; Teplow, D.B.; & Hess W.M. 2000,Cryptocandin, a potent antimycotic from endophytic fungus Cryptosporiopsis quercina. Microbiology 145: 1919-1926.
Tejesvi, M.V.; Nalini, M.S.; Mahesh, B.; Prakash, H.S.; Kini, K.R.; Shetty, H.S.; & Ven, S. 2007,New Hopes From Endhopythic Fungal Secondary metabolite. Bol. Soc. QuÃm. Méx., 1(1): 19-26
Tan, R.X.; & Zou, W.X. 2001,Endophytes: a rich source of functional metabolites. Nat. Prod. Rep.18 : 448-459