Antioxidant Activity Test of Effervescent Granules Morinda citrifolia L Leaf Extract with DPPH Free Radical Absorption Method

Authors

  • Muthmainah Tuldjanah STIFA Pelita Mas Palu Author
  • Niluh Puspita Dewi Author
  • Dian Rahmawati Author

DOI:

https://doi.org/10.30872/j.trop.pharm.chem.v5i4.260

Keywords:

Antioxidant activity, DPPH, Effervescent granules, Morinda citrifolia. L leaf

Abstract

Morinda citrifolia. L leaf is a plant that has the potential as an antioxidant due to the presence of compounds in the form of flavonoids and other phenolic compounds that can function as natural antioxidants. In connection with this, research was carried out to Morinda citrifolia. L formulate leaf extract in the form of effervescent granules. Morinda citrifolia leaf extract was macerated with ethanol 96% as solvent. Phytochemical screening showsthat the extract contains flavonoids, tannins, saponins and alkaloids. The extract was formulated with various concentrations of F1 (20%), F2 (25%), F3 (4%). Determination of antioxidant activity using the DPPH free radical immersion method. The results showed that the concentration in the granules influenced antioxidant activity with IC50 values of 109.05 ppm, 101.33 ppm and 73.28 ppm, respectively

References

Arief, S. 2007. Radikal Bebas. [Artikel] Ilmu Kesehatan Anak FK UNAIR.. RSU Dr. Soetomo, Surabaya.

Siagian., Priska. 2012. Keajaiban Antioksidan. PT. Gramedia Pustaka Utama. Jakarta. Hal:1- 19.

E. Syahruddin, H. Abbas, E. Purwati, dan Y. Heryandi. 2012. Aplikasi Mengkudu Sebagai Sumber Antioksidan Untuk Mengatasi Stress Ayam Broiler Di Daerah Tropis. Jurnal Peternakan Indonesia Vol. 14 (3). Fakultas Peternakan Universitas Andalas Kampus Unand Limau Manis Padang.

Lingga, L. 2012. The Healing Power of Antioxidant. PT Elex Media. Jakarta. 28-31, 69, 87-91, 109-111.

Anonim. 2014 Farmakope Indonesia, Edisi V. Departemen Kesehatan Republik Indonesia. Jakarta. 53, 519, 601

Ansel, H.C. Pengantar Bentuk Sediaan Farmasi. Diterjemahkan oleh Farida Ibrahim. 1989. Edisi IV. UI Press. Jakarta. 202-203, 214-2017. Dalam W, Sinta. 2014. Uji Aktivitas Antioksidan Granul Effervescent Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus)

Ganjar., Ibnu dan Rohman. 2012. Kimia Farmasi Analisis. Pustaka Pelajar. Yogyakarta. L: 220-262.

Jannah, R. N., Fadraersada, J., Meylina, L., & Ramadhan, A. M. (2018). Formulasi Granul Antioksidan Ekstrak Etanol Daun Sirsak (Anonna muricata Linn.) Menggunakan Metode Granulasi Basah. Proceeding of Mulawarman Pharmaceuticals Conferences, 8(1), 97-103. https://doi.org/10.25026/mpc.v8i1.310

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Published

2021-12-31

How to Cite

Antioxidant Activity Test of Effervescent Granules Morinda citrifolia L Leaf Extract with DPPH Free Radical Absorption Method. (2021). Journal of Tropical Pharmacy and Chemistry , 5(4), 365–368. https://doi.org/10.30872/j.trop.pharm.chem.v5i4.260