The Potential Of Citronella (Cymbopogon Nardus (L.) Rendle) Essential Oil In Inhibiting The Formation Of Escherichia Coli And Candida Albicans Biofilms

Mentarry Bafadal; Hasyrul  Hamzah; Supriatno Salam; Fajar Prasetya

doi:10.30872/jtpc.v9i2.303

Authors

Mentarry Bafadal Fakultas Farmasi Universitas Mulawarman Author
Hasyrul Hamzah Faculty of Pharmacy, Universitas Muhammadiyah Kalimantan Timur, Samarinda 75124, Indonesia Author
Supriatno Salam Department of Pharmacognosy and Medicinal Chemistry, Faculty of Pharmacy, Mulawarman University, Samarinda, East Borneo, Indonesia Author
Fajar Prasetya Department of Pharmacology, Faculty of Pharmacy, Mulawarman University, Samarinda, East Borneo, Indonesia Author https://orcid.org/0000-0002-1020-0423

DOI:

https://doi.org/10.30872/jtpc.v9i2.303

Keywords:

Biofilm , Citronella, E. coli, C. albicans

Abstract

Indonesia is a tropical country that has very high biodiversity, one of which is the citronella plant (Cymbopogon nardus (L.) Rendle). Citronella leaves have a strong distinctive aroma and essential oils are odorous compounds found in the plant. This study aims to identify the components of compounds in essential oils in citronella oil and the potential for antibiofilm against Escherichia coli and Candida albicans. Essential oils were obtained through a distillation process. Furthermore, they were tested in four concentration series (0.125%; 0.25%; 0.5%; 0.1%) to measure the activity of the ability to inhibit the formation of E. coli and C. albicans biofilms using the microdilution method. The results of the antibiofilm test were analyzed based on optical density to calculate the percentage of inhibition. Citronella essential oil with the highest concentration of 1% showed inhibition of biofilm formation against E. coli and C. albicans of 84% and 79% respectively. Citronella essential oil can inhibit the formation of E. coli and C. albicans biofilms.

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