Prosfektif Metode Sampel Darah Kering dalam Bioanalisis

Authors

  • Supandi Supandi Fakultas Farmasi dan Sains, Uhamka, Jakarta, Indonesia Author

Keywords:

dried blood spot, bioanalysis, pharmacokinetic, therapeutic drug monitoring

Abstract

Biosampling of dried blood spot method became lately very interested in bioanalysis, some of the advantages given in this method compared to conventional venous canulla (venipuncture); less invasive making it more pleasant for the patient or subject, requires small volume, requires simple transportation process and storage did not need special equipment, suod stabilizes analit and reduces risk of infection. The method of dried blood spot is done by invasive light on the finger or heel prick and then spike on filter paper and dried at room temperature or under nitrogen flow with controlled humidity and stored in bag with desiccant packages, than it analyzed using validation bioanalyzing method. Dried blood spot method can be applied on bioanalysis test for pharmacokinetic, toksikokinetic , epidemiologic and Teurapeutic drug monitoring.

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References

1. Borremans B. (2014) Ammonium improves elution of fixed dried blood spots without affecting immunofluorescence assay quality. Trop. Med. Int. Health. DOI: 10.1111/tmi.12259

2. Chambers A.G., Andrew J.P., Juncong Y., Alexander G.C., & Christoph H.B. (2013) Multiplexed Quantitation of Endogenous Proteins in Dried Blood Spots by Multiple Reaction Monitoring - Mass Spectrometry. The American Society for Biochemistry and Molecular Biology, 12 (3), pp. 781–791

3. Clark T.G & Julian J.H. (2011) Utilization of DBS within drug discovery: a simple 2D-LC–MS/MS system to minimize blood- and paper- based matrix effects from FTA elute™ DBS. Bioanalysis, 3(11), pp. 1253–1270

4. Clavel M.S., & Petra H. (2015) Analysis of metformin, sitagliptin and creatinine in human dried blood spots. Journal of Chromatography B, 997, pp. 218–228

5. Dainty T.C., Richmond E.S., Davies

I. & Blackwell M.P. (2012) Dried blood spot bioanalysis: an evaluation of techniques and opportunities toxicokinetic studies. Int J Toxicol. 31(1), pp 4-13

6. Déglon J., Aurélien T., Patrice M., & Christian S. (2012) Direct analysis of dried blood spots coupled with mass spectrometry: concepts and biomedical applications. Anal. Bioanal. Chem., 402, pp. 2485–2498

7. Demirev A.F. (2013) Dried blood spots: Analysis and applications. Anal.Chem. 85, 779

8. Dieter Z., Stephan H., Beatrice B., Stephan S., Christoph F., & Matthias

L. (2013) Internal standard application to dried blood spots by spraying: investigation of the internal standard distribution. Bioanalysis, 5(6), pp. 711–719

9. Edwards R.L., Andrew J.C., Mark B., Paul G., Josephine B., & Helen J.C. (2011) Hemoglobin Variant Analysis via Direct Surface Sampling of Dried Blood Spots Coupled with High - Resolution Mass Spectrometry. Anal. Chem., 83, pp. 2265–2270

10. EMA (2011) Guideline on bioanalytical method validation European Medicine Agency London:

pp. 4-10

11. Enaksha R.W., Basira G.A., Naijia H.H., John W.R., Jennifer L.H., Kenneth J.R., Everett J.P., & Ajai

K.C. (2011) Dried blood spot sampling: coupling bioanalytical feasibility, blood–plasma partitioning and transferability to in vivo preclinical studies. Bioanalysis, 3(14), pp. 1635–1646

12. EQA (2005) Blood Collection and Handling Dried Blood Spot (Modul 14). Available at: http://www.who.int/diagnostics_labor atory/documents/guidance/pm_modul e14.pdf [10 September 2015].

13. Evans C., Mark A., Peter B., Jeffrey D., Christopher A.J., Wenkui L., Steve L., Luca M., Timothy O., Philip T., Xiaomin W., Enaksha W., John W., Eric W., & Patricia Z. (2015) Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group. The AAPS Journal, Vol. 17, No. 2, pp. 292-300

14. FDA (2001) Guidance for Industry Bioanalytical Method Validation.

Food and Drug Administration United States of America: Department of Health and Human Services.

15. FDA. 510(K) SUMMARY. Available

at: http://www.accessdata.fda.gov/cdrh_ docs/pdf12/k121864.pdf [8 oktober

2015]

16. Ingels A., Lambert W.E. & Stove

C.P. (2010) Determination of gamma- hydroxybutyric acid in dried blood spots using a simple GC–MS method with direct ‘on spot’ derivatization. Anal. Bioanal. Chem. 398(5), pp. 2173–2182

17. Jager N.G.L., Hilde R., Jan H.M.S., & Jos H.B. (2014) Determination of tamoxifen and endoxifen in dried blood spots using LC–MS/MS and the effect of coated DBS cards on recovery and matrix effects. Bioanalysis, 6(22), pp. 2999–3009

18. Jager N.G.L., Hilde R., Jan H.M.S., & Jos H.B. (2014) Procedures and practices for the validation of bioanalytical methods using dried blood spots: a review. Bioanalysis. 6(18), pp. 2481–2514

19. Kesel P.M.M., Nele S., Sara C., Willy E.L., & Christophe P.S. (2013) Hemato-critical issues in quantitative analysis of dried blood spots: challenges and solutions. Bioanalysis, 5(16), pp. 2023–2041

20. La Marca G, Giocaliere E. & Villanelli F. (2012) Development of an UPLC–MS/MS method for the determination of antibiotic ertapenem on dried blood spots. J. Pharm. Biomed. Anal. 61, pp. 108–113

21. Liang X., Yang L., Berezhkovskiy L, Liederer B., Nguyen T, Jia Y., Schweiger W.,Dean B. & Deng Y. (2011) Evaluation of dried blood spot sampling following cassette dosing in drug discovery. Bioanalysis, 3, 2291.

22. Liu G., Heidi M.S., & Qin C.J. (2011)

Internal standard tracked dilution to overcome challenges in dried blood

spots and robotic sample preparation for liquid chromatography/tandem mass spectrometry assays. Rapid Commun. Mass Spectrom, 25, pp. 1250–1256

23. Liu G., Ji Q.C., Jemal M., Tymiak

A.A. & Arnold M.E. (2011)

Approach to evaluating dried blood spot sample stability during drying process and discovery of a treated card to maintain analyte stability by rapid on-card pH modification. Anal. Chem. 83, 9033.

24. Maria C.H., Emile H.M., and Jan A.O., 2015. Hematocrit-independent recovery of immunosuppressants from DBS using heated flow-through desorption. Bioanalysis, 7(16), pp. 2019–2029

25. Martin N.J. & Helen J.C. (2014) Challenges and opportunities in mass spectrometric analysis of proteins from dried bloodspots. Expert Rev. Proteomics, 11(6), pp. 685–695

26. Neil Spooner (2013). A dried blood spot update: still an important bioanalytical technique. Bioanalysis, 5(8), pp. 879–883

27. Nikolay Y., osée M., Sylvain L., Jean N.M., Annik B., Milton F., Marianne R., Pascal G., Marc L., Robert B.M. & Fabio G. (2010) Determination of naproxen using DBS: evaluation & pharmacokinetic comparison of human plasma versus human blood DBS. Bioanalysis, 2(8), pp. 1501–

1513

28. Odoardi S., Luca A. & Sabina S.R. (2014). Simplifying sample pretreatment: Application of dried blood spot (DBS) method to blood samples, including postmortem, for UHPLC–MS/MS analysis of drugs of abuse. Forensic Science International, 243, pp. 61–67

29. Oliveira R.V., Jack H. & Enaksha W. (2014) Fully-Automated Approach for Online Dried Blood Spot Extractionand Bioanalysis by Two- Dimensional-Liquid

ChromatographyCoupled with High- Resolution Quadrupole Time-of- Flight Mass Spectrometry. Anal. Chem. 86, pp. 1246−1253

30. O’Mara M., Hudson B.C., Olson K., Yueh Y., Dunn J. & Spooner N. (2011) The effect of hematocrit and punch location on assay bias during quantitative bioanalysis of dried blood spot samples. Bioanalysis, 3(20), pp. 2335–2347

31. Philip D. & Neil S. (2010) The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs. Bioanalysis, 2(8), pp. 1385–1395

32. Rizwana Q., Raka J. & Atul A. (2013) The use of dried blood spot samples in screening drugs of abuse. Pharmacology & Pharmacy. 4, pp. 152-159

33. Rowland M. & Gary T.E. (2010) Use of Dried Blood Spots in Drug Development: Pharmacokinetic Considerations. The AAPS Journal, Vol. 12, No. 3, pp. 290-293

34. Sharma A., Swati J., Mahendra S. & Jawahar L. (2014) Dried blood spots: Concepts, present status, and future perspectives in bioanalysis. Drug Test. Analysis. DOI 10.1002/dta.1646

35. Soto M., Roger P., Valerie A., Mylowagner, Ronya P., Manuel P., James M., Christopher A.J., Kevin

L.S. & Marc W.R. (2014) Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies. Bioanalysis, 6(16), pp. 2135–2146

36. Tanna S., Dennis B. & Graham L. (2015) LC-HRMS Analysis of Dried Blood Spot Samples for Assessing Adherence to Cardiovascular Medications. J. Bioanal. Biomed. Volume 7(1), pp. 001-068

37. Timmerman P., White S., Globig S., Ludtke S., Brunet L. & Smeraglia J. (2011) EBF recommendation on the validation of bioanalytical methods for dried blood spots. Bioanalysis.;3:1567–75.

38. Vu D.H., Koster R.A., Bolhuis M.S., Greijdanus B., Altena R.V., Nguyen D.H, Brouwers J.R.B.J., Uges D.R.A. & CAlffenaar J.W. (2014) Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC–MS/MS.Talanta, 121, pp. 9–17

39. Wenkui Li and Francis L.S.T., 2010. Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomed. Chromatogr., 24,

pp. 49–65

40. Wenkui Li., John D., Paul M., Jimmy

F. & Francis L.S.T. (2015) LC–

MS/MS bioanalysis of loratadine (Claritin in dried blood spot (DBS) samples collected by subjects in a clinical research study. Journal of Chromatography B, 983–984, pp. 117–124

41. Wilhelm A.J., Jeroen C.G., Burger D. & Eleonora L.S. (2014) Therapeutic Drug Monitoring by Dried Blood Spot: Progress to Date and Future Directions. Clin. Pharmacokinet, 53,

pp. 961–973

42. Zanet D.L., Saberi L., Oliveira L., Sattha B., Gadawski I. & Cote. H.C. (2013) Blood and dried blood spot telomere length measurement by qPCR: Assay considerations. PLoS One, 8, e57787.

43. Zhang Z., Wei X., Nicholas E.M., Graham R.C. & Zheng O. (2012) Silica Coated Paper Substrate for Paper-Spray Analysis of Therapeutic Drugs in Dried Blood Spots. Anal. Chem. 84, pp. 931−938

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Published

2016-06-30

How to Cite

Prosfektif Metode Sampel Darah Kering dalam Bioanalisis. (2016). Journal of Tropical Pharmacy and Chemistry , 3(3), 224–231. https://jtpc.ff.unmul.ac.id/index.php/jtpc/article/view/89

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