Formulation and Evaluation of N-Hexane Fraction of Libo Fruit based Emulgel for Sunscreen
DOI:
https://doi.org/10.30872/j.trop.pharm.chem.v7i2.166Keywords:
emulgel, Ficus variegata Blume, libo, sunscreenAbstract
Libo fruit (Ficus variegata Blume) has activity as a sunscreen. Topical form of certain pharmaceuticals can be used to protect the skin from sun exposure. This study aims to determine the best gel-emulsion formula from the libo’s N-Hexane fraction, its stability, and its sunscreen activity. The formula was consist gelling agents variations type and concentration, i.e. carbopol 940 and hydroxypropyl methylcellulose (HPMC). The best formula were chosen based on physicochemical characteristics. the freeze-thaw test deployed to check the stability, and the sunscreen activity was tested using UV-Vis spectrophotometry. The results showed that the best formula was formula 1 with carbopol 940 (1%), there were no changes in physicochemical characteristics during the stability test, and experienced a decrease in sunscreen activity after the stability test.
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Lushaini, S. .; Wibowo, M. A.; Ardiningsih., P. Kandungan Total Fenol, Aktivitas Antioksidan Dan Sitotoksik Daun Kedadai (Ficus Variegata Blume). J. Kim. Khatulistiwa, 2015, 4 (2), 1–5.
Rijai, L. Potensi Tumbuhan Libo (Ficus Variegata Blume) Sebagai Sumber Bahan Farmasi Potensial. J. Trop. Pharm. Chem., 2013, 2 (3), 166–179.
Kusuma, I. W.; Murdiyanto; A., E. T.; Syafrizal; Kim, Y. Antimicrobial and Antioxidant Properties of Medicinal Plants Used by the Bentian Tribe From Indonesia. Food. Sci. Hum. Wellness, 2014, 3, 191–196.
Hardina; Puspha, M.; Rusli, R.; Muflihah, F.; Rahmadani, A. Profil Kromatografi Senyawa Aktif Antioksidan Dan Antibakteri Fraksi N-Heksana Daun Libo (Ficus Variegata Blume). J. Trop. Pharm. Chem., 2015, 3 (2), 124–130.
Hardenia, A.; Jayronia, S.; Jain, S. K. Emulgel: An Emergent Tool in Topical Drug Delivery. Int. J. Pharm. Sci. Res., 2014, 5 (5), 1653–1660.
Kumari, A.; Singh, A.; Saurabh, S. S.; Rathore, K. S.; R. Issarani. Formulation and Evaluation of Lycopene Emulgel. Indo Am. Pharm. Sci., 2015, 2 (6), 1013–1027.
Martin, A.; Swarbick, J.; Cammarata, A. Farmasi Fisik (Terjemahan Dari Physical Pharmacy, Physical Chemical Principles in the Pharmaceutical Sciences); Universitas Indonesia Press: Jakarta, 2008.
Priani, S. E.; Humanisya, H.; Darusman, F. Development of Sunscreen Emulgel Containing Cinnamomum Burmannii Stem Bark Extract. Int. J. Sci. Res., 2012, 3, 2338–2341.
Levin, J.; H., M. Human Skin Buffering Capacity. Journal of Skin. Res. Technol., 2007, 14, 121–126.
Pratama, A. W.; A. Karim, Z. Uji SPF in Vitro Dan Sifat Fisik Beberapa Produk Tabir Surya Yang Beredar Di Pasaran. Maj. Farmasetik, 2015, 11 (1), 275–283.
Aryani, R. Formulasi Dan Uji Stabilitas Krim Kombinasi Alfa Tokoferol Asetat Dan Etil Vitamin C Sebagai Pelembab Kulit. J. Kesehat. Bakti Tunas Husada, 2015, 14 (1), 38–46.
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Copyright (c) 2025 Yuni Dwi Anjarwati, Lisna Meylina, Rolan Rusli (Author)
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